反应详情

This acylation is performed in the following manner: 1.08 g (10-2 moles) of ethyl chloroformate in 5 ml of anhydrous ethyl acetate are added dropwise to a solution containing 10-2 moles of benzaldehyde (2-hydroxyethyl)hydrazone and 0.79 g (10-2 moles) of anhydrous pyridine in 20 ml of anhydrous ethyl acetate, with stirring in the cold. The reaction mixture is left at 0° C. with stirring for 2 hours and then it is filtered. The product obtained is washed with 10 ml of water and then dried and recrystallized from a mixture of ethyl acetate and petroleum ether. It has a melting point of 69.5° C. The reaction yield is 62%.

1. waitThe reaction mixture is left at 0° C.
2. stirringwith stirring for 2 hours
3. filtrationit is filtered
4. customThe product obtained
5. washis washed with 10 ml of water
6. customdried
7. customrecrystallized from a mixture of ethyl acetate and petroleum ether
8. customThe reaction yield is 62%