HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → Methyl 4-(3-(2-hydroxyphenyl)propyl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 18973894 | HCID 18973894 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | Methyl 4-(3-(2-hydroxyphenyl)propyl]benzoate | HCID 18973735 | — |
Reaction Steps
A mixture of 4-[3-(2-benzyloxyphenyl)-3-carbonyl-1(E)-propenyl]benzoate (35 g), 10% Pd-carbon (7 g), acetic acid (350 mil) and trifluoroacetic acid (7 ml) was warmed at 30° C. under 10 atm. of hydrogen for 18 hours, filtered and the filtrates evaporated. The residue was triturated with hexane and dried to give methyl 4-(3-(2-hydroxyphenyl)propyl]benzoate (26 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05811459 |
| Source dataset | uspto-grants-1998_09 |
| ORD ID | ord-08fc2db3bfaf42e0bb71aec567964b20 |
| Source note | uspto-grants-1998_09 |