HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3-(2-Benzyloxyphenyl)propyl]benzoic acid → 4-[2-(2-Benzyloxyphenyl)-(Z)-ethenyl]-2-methoxybenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3-(2-Benzyloxyphenyl)propyl]benzoic acid | HCID 18973764 | — |
| Reactant | 4-[2-(2-benzyloxyphenyl)-(E)-ethenyl]-2-methoxybenzoic acid | HCID 18973900 | — |
| Reactant | Methyl 4-[3-(2-benzyloxyphenyl)propyl)benzoate | HCID 18973910 | — |
| Reactant | Methyl 4-[2-(2-benzyloxyphenyl)-(Z)-ethenyl]-2-methoxy-benzoate | HCID 70347226 | — |
| Product | 4-[2-(2-Benzyloxyphenyl)-(Z)-ethenyl]-2-methoxybenzoic acid | HCID 70346838 | — |
Reaction Steps
Methyl 4-[2-(2-benzyloxyphenyl)-(Z)-ethenyl]-2-methoxy-benzoate (obtained from methyl 4-[2-(2-benzyloxyphenyl)-(Z)-ethenyl]-2-hydroxybenzoate as described in Example 14) was converted to 4-[2-(2-benzyloxyphenyl)-(E)-ethenyl]-2-methoxybenzoic acid (containing 15% of the (Z) isomer and obtained as a gum; negative FAB mass peak 359) using the method described in Example 1 for the conversion of methyl 4-[3-(2-benzyloxyphenyl)propyl]benzoate to 4-[3-(2-benzyloxyphenyl)-propyl]benzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05811459 |
| Source dataset | uspto-grants-1998_09 |
| ORD ID | ord-aecf430af043401fb443a1deb830d77a |
| Source note | uspto-grants-1998_09 |