HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Isobutylpiperazine dihydrochloride → 1-(2-Methylpropyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Isobutylpiperazine dihydrochloride | HCID 2759388 | — |
| Solvent | Sodium hydrochloride | HCID 23872008 | — |
| Product | 1-(2-Methylpropyl)piperazine | HCID 2052052 | 95.1% |
Reaction Steps
To 1-isobutylpiperazine dihydrochloride(69.5 g) was added 10% aqueous solution of sodium hydrochloride(100 ml) and the mixture was extracted with ether. After being concentrated, the extract was distilled under a vacuum(bp 172°-174° C./5 mmHg), thereby yielding 43.7 g of 1-isobutylpiperazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05814634 |
| Source dataset | uspto-grants-1998_09 |
| ORD ID | ord-189a9b11a9ba4088b4d9ca7c9289457b |
| Source note | uspto-grants-1998_09 |