1-Phenylpiperazine → HCID 86753178, compound

Participants

Reaction Steps

A mixture of 2-(3-chloropropionylamino)benzyltriphenylphosphonium bromide (2.70 g, 5 mmol) and phenylpiperazine (1.70 g, 10 mmol) in acetonitrile (85 ml) was heated at reflux for 2.5 h. The mixture was cooled to room temperature and filtered and the filtrate evaporated in vacuo to give 2-(3-[4-phenylpiperazin-1-yl]propionylamino) benzyltriphenylphosphonium bromide as a white solid (3.1 g, 93%).

Provenance & Evidence