2-Amino-3-methylbenzoic acid → HCID 18971521, compound

Participants

Reaction Steps

2.00 g (9.19 mmol) of 4-chlorobenzenesulfonylisocyanate and 1.26 g (8.33 mmol) of 2-amino-3-methylbenzoic acid were treated in the same way as in Example 1 to obtain 2.86 g of the above-identified compound (yield 98.0%). Properties: colorless crystal, Melting point: 221°-225° C., PMR (δppm, DMSO-d6): 2.32 (3H,s), 7.12 (1H,t), 7.51 (1H,d), 7.72 (1H,d), 7.76 (2H,d), 8.19 (2H,d), 11.10 (1H,br).

Provenance & Evidence