HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-4-isothiocyanato-2-(trifluoromethyl)benzene → 1-[4-(6-Phenyl-3-pyridazylthio)phenyl]-3-(4-chloro-3-trifluoromethylphenyl)thiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-4-isothiocyanato-2-(trifluoromethyl)benzene | HCID 520026 | — |
| Reactant | 3-(4-Aminophenylthio)-6-phenylpyridazine | HCID 18971661 | — |
| Product | 1-[4-(6-Phenyl-3-pyridazylthio)phenyl]-3-(4-chloro-3-trifluoromethylphenyl)thiourea | HCID 18971682 | 69.1% |
Reaction Steps
3-(4-aminophenylthio)-6-phenylpyridazine (7.0 mmoles, 2.0 g) and 4-chloro-3-trifluoromethylphenylisothiocyanate (7.0 mmoles, 1.66 g) were reacted according to procedure C to yield of the title compound 2.5 g, 69%. Mass Spec (FD) 516. Calculated for C24H16ClF3 N4O2S2 : C, 55.76; H, 3.12; N, 10.84. Found: C, 55.98 H, 3.19; N, 10.78.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05814646 |
| Source dataset | uspto-grants-1998_09 |
| ORD ID | ord-972c0db6ff35466b9ed9810581237fa1 |
| Source note | uspto-grants-1998_09 |