Benzoic acid, 4-((5,6,7,8-tetrahydro-5,5-dimethyl-8-oxo-2-naphthalenyl)ethynyl)-, ethyl ester → HCID 17896148, compound

Participants

Reaction Steps

Employing the same general procedure as for the preparation of 4- [(5,6,7,8-tetrahydro-8,8-dimethyl-5-oxonaphth-2-yl ) ethynyl]benzoic acid (Compound 7 ) , 500 mg (1.45 mmol) of ethyl 4-[(5,6,7,8 -tetrahydro-8,8-dimethyl-5-oxonaphth-3-yl) ethynyl]benzoate (Compound 2 ) was converted into the title compound using 4 ml (4 mmol) of LiOH (1N aqueous solution).

Provenance & Evidence