HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-Amino-4-phenyl-2-butanone hydrochloride (1:1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Acetamide, N-[2-oxo-1-(phenylmethyl)propyl]- | HCID 227936 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Amino-4-phenyl-2-butanone hydrochloride (1:1) | HCID 13342250 | 81% |
Reaction Steps
A mixture of 3-acetylamino-4-phenyl-2-butanone (12.5 g), 6N HCl (50 ml) and ethanol (50 ml) was stirred under refluxing conditions for 18 hours. The reaction mixture was concentrated under reduced pressure to yield 3-amino-4-phenyl-2-butanone hydrochloride (9.8 g, 81%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05489602 |
| Source dataset | uspto-grants-1996_02 |
| ORD ID | ord-c78edbd5751a4a8eba828c8a9ca9e654 |
| Source note | uspto-grants-1996_02 |