Hydrogen Bromide → HCID 18990377, compound

HRID 2395721Notes

Reaction equation

HRID 2395721 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]=1[OH:10])[CH2:5]O.[BrH:14]>>[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]=1[OH:10])[CH2:5][Br:14]

Participants

3

Reactant 2

HCID 260Hydrogen BromideHCID 189903745-(Hydroxymethyl)-3-nitrobenzene-1,2-diol

Product 1

HCID 18990377HCID 18990377, compound

Procedure

12.2 g of 3,4-dihydroxy-5-nitrobenzyl alcohol was dissolved in 100 ml of 47% hydrobromic acid at 50° C. After cooling the product was filtered and washed with 47% hydrobromic acid. The crude product was dissolved in dichloromethane and dried over Na2SO4. The mixture was filtered and the solvent was evaporated in vacuo. Yield 7.1 g.

Workup

  1. temperatureAfter cooling the product
  2. filtrationwas filtered
  3. washwashed with 47% hydrobromic acid
  4. dissolutionThe crude product was dissolved in dichloromethane
  5. dry with materialdried over Na2SO4
  6. filtrationThe mixture was filtered
  7. customthe solvent was evaporated in vacuo

Sources & evidence

ORD record
ord-cf062d642a7a464c8dd42b152e4bc251
Source dataset
uspto-grants-1996_02
Patent number
US05489614

Reaction notes

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