HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Fluoroindole-2-carboxylic acid → 5-Fluoro-1H-indole-2-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Fluoroindole-2-carboxylic acid | HCID 1820 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Product | 5-Fluoro-1H-indole-2-carbonyl chloride | HCID 15167806 | — |
Reaction Steps
5-Fluorindole-2-carboxylic acid is dissolved in oxalylchloride and stirred 24 hr at 20°-25° in the dark. The reaction mixture is concentrated under reduced pressure to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05489593 |
| Source dataset | uspto-grants-1996_02 |
| ORD ID | ord-eb4360aaf731474cbf13c28d395eb167 |
| Source note | uspto-grants-1996_02 |