HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3,7-Dichloroquinolin-8-carbonyl Chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Quinclorac | HCID 91739 | — |
| Product | 3,7-Dichloroquinolin-8-carbonyl Chloride | HCID 13090840 | 95.7% |
Reaction Steps
3,7-Dichloro-8-quinolinecarboxylic acid(20 g, 82 mmol) was added to thionyl chloride(80 ml), and the mixture refluxed for 3 hours and concentrated under reduced pressure to afford the desired product(20.6 g, yield=95.7%) as a light brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05489687 |
| Source dataset | uspto-grants-1996_02 |
| ORD ID | ord-a3d5fd81fa9442d3a1d98dde0c6573c8 |
| Source note | uspto-grants-1996_02 |