Phloroglucinol → 5,7-Dihydroxy-4-propylcoumarin

HRID 2395863Notes

Reaction equation

HRID 2395863 reaction equation
[C:1]([CH2:6][C:7](OCC)=[O:8])(=O)[CH2:2][CH2:3][CH3:4].[C:12]1([CH:20]=[C:18]([OH:19])[CH:17]=[C:15]([OH:16])[CH:14]=1)[OH:13]>>[OH:13][C:12]1[CH:20]=[C:18]([OH:19])[CH:17]=[C:15]2[C:14]=1[C:1]([CH2:2][CH2:3][CH3:4])=[CH:6][C:7](=[O:8])[O:16]2

Participants

3

Reactant 2

HCID 359PhloroglucinolHCID 238498Ethyl 3-oxohexanoate

Product 1

HCID 53912605,7-Dihydroxy-4-propylcoumarin

Procedure

condensing ethyl butyrylacetate and phloroglucinol in the presence of an acid catalyst to form 5,7-dihydroxy-4-propylcoumarin;

Sources & evidence

ORD record
ord-088abfb292534d8fb09e7e07307f84d4
Source dataset
uspto-grants-1996_02
Patent number
US05489697

Reaction notes

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