Trifluoroacetic acid → HCID 18990879, compound

HRID 2395872Notes

Reaction equation

HRID 2395872 reaction equation
C(OC([NH:8][CH:9]([C:11]1[CH:16]=[CH:15][C:14]([N:17]2[CH2:21][CH2:20][CH:19]([C:22]3[CH:27]=[CH:26][C:25]([CH2:28][CH2:29][C:30]([O:32][CH3:33])=[O:31])=[CH:24][CH:23]=3)[C:18]2=[O:34])=[CH:13][CH:12]=1)[CH3:10])=O)(C)(C)C.FC(F)(F)C(O)=O>C(Cl)Cl>[NH2:8][CH:9]([C:11]1[CH:12]=[CH:13][C:14]([N:17]2[CH2:21][CH2:20][CH:19]([C:22]3[CH:23]=[CH:24][C:25]([CH2:28][CH2:29][C:30]([O:32][CH3:33])=[O:31])=[CH:26][CH:27]=3)[C:18]2=[O:34])=[CH:15][CH:16]=1)[CH3:10]

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 18991070HCID 18991070, compound

Product 1

HCID 18990879HCID 18990879, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Prepared from 1-[4-[1-[(tert.butyloxycarbonyl)-amino]ethyl]-phenyl]-3-[4-(2-methoxycarbonyl-ethyl)-phenyl]-pyrrolidin-2-one by stirring for 2 hours in a 1:1 mixture of methylene chloride and trifluoroacetic acid.

Sources & evidence

ORD record
ord-3cf97369a3804fdfb17f6dcce1c8a66b
Source dataset
uspto-grants-1996_02
Patent number
US05489693

Reaction notes

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