HCID 10489281, compound → HCID 10773751, compound

Participants

Reaction Steps

7.0 g of 3-acetoxy-2-isopropyl-1-propanesulfonamide was dissolved in 50 ml of methanol. While stirring the solution at room temperature (15° to 20° C.), 6.5 g of 28 w/w % sodium methoxide was added, and reaction was carried out for 30 minutes. The reaction mixture was concentrated to dryness; the residue was then subjected to column chromatography using 100 g of silica gel and eluted with chloroform:methanol (9:1) to yield 4.4 g of the title compound.

Provenance & Evidence