HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → N-thiomorpholinocarbonyl-N,N'-dimethylethylenediamine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-t-butoxycarbonyl-N'-thiomorpholinocarbonyl-N,N'-dimethylethylenediamine | HCID 18988036 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | N-thiomorpholinocarbonyl-N,N'-dimethylethylenediamine hydrochloride | HCID 18988040 | — |
Reaction Steps
N-t-Butoxycarbonyl-N'-thiomorpholinocarbonyl-N,N'-dimethylethylenediamine (4.92 g) was dissolved in a solution of 4N hydrogen chloride in ethyl acetate (60 ml) under ice-bath cooling. After being stirred at ambient temperature for 30 minutes, the solution was concentrated in vacuo to give N-thiomorpholinocarbonyl-N,N'-dimethylethylenediamine hydrochloride (3.93 g) as an oil. Rf: 0.25 (chloroform:methanol:acetic acid, 8:1:1, V/V)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05491132 |
| Source dataset | uspto-grants-1996_02 |
| ORD ID | ord-76fcb396482947d9a91b1bcbd561fbe9 |
| Source note | uspto-grants-1996_02 |