HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorine → 2-Chloroamino-5-trifluoromethylpyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorine | HCID 24526 | — |
| Reactant | 2-Amino-5-(trifluoromethyl)pyridine | HCID 735862 | — |
| Product | 2-Chloroamino-5-trifluoromethylpyridine | HCID 18988854 | — |
Reaction Steps
The method according to claim 1, wherein 2-amino-5-trifluoromethylpyridine is reacted with chlorine to form 2-chloroamino-5-trifluoromethylpyridine, which is then subjected to a rearrangement reaction in the presence of at least one carboxylic acid selected from the group consisting of formic acid, acetic acid and propionic acid to obtain 2-amino-3-chloro-5-trifluoromethylpyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05491239 |
| Source dataset | uspto-grants-1996_02 |
| ORD ID | ord-7e816c801dcc447bb4138eda1642160d |
| Source note | uspto-grants-1996_02 |