HCID 10825133, compound → HCID 10559045, compound

HRID 2396488Notes

Reaction equation

HRID 2396488 reaction equation
[CH3:1][N:2]([CH2:10][CH2:11][NH:12][CH:13]([CH:17]1[CH2:19][CH2:18]1)[CH:14]1[CH2:16][CH2:15]1)CC1C=CC=CC=1>C(O)C.[Pd]>[CH3:1][NH:2][CH2:10][CH2:11][NH:12][CH:13]([CH:17]1[CH2:19][CH2:18]1)[CH:14]1[CH2:15][CH2:16]1

Participants

4

Reactant 1

HCID 10825133HCID 10825133, compound

Product 1

HCID 10559045HCID 10559045, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Conditions

Temperature
45 °C

Procedure

5.8 g of the compound obtained in Step b, in 30 ml of absolute ethanol, and 100 mg of 10% palladium-on-carbon are stirred and heated at 45° C. under a hydrogen atmosphere for 3 hours. The solvent is evaporated off. After customary treatment of the organic phase, the desired crude product is purified by distillation.

Workup

  1. customThe solvent is evaporated off
  2. distillationAfter customary treatment of the organic phase, the desired crude product is purified by distillation

Sources & evidence

ORD record
ord-31a2d50cd43f4986bc071197bce7fb63
Source dataset
uspto-grants-1996_02
Patent number
US05492912

Reaction notes

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