2-Bromopropane → HCID 9859549, compound

HRID 2396489Notes

Reaction equation

HRID 2396489 reaction equation
C(O[C:4]([CH:6]1[CH2:11][NH:10][CH2:9][CH2:8][NH:7]1)=O)C.[CH:12](Br)([CH3:14])[CH3:13]>>[CH:12]([N:7]1[CH2:8][CH2:9][N:10]([CH:6]([CH3:11])[CH3:4])[CH2:11][CH:6]1[C:4]1[NH:7][CH2:8][CH2:9][N:10]=1)([CH3:14])[CH3:13]

Participants

3

Reactant 2

HCID 63582-BromopropaneHCID 10633257Ethyl Piperazine-2-carboxylate

Product 1

HCID 9859549HCID 9859549, compoundYield 35%

Procedure

Reacting 2-ethoxycarbonylpiperazine with 2,2 aquivalents of isopropyl bromide in the same conditions as for example 21, and treating the obtained product in the same conditions as for example 1, step d, the desired product is obtained.

Workup

  1. additiontreating the obtained product in the same conditions as for example 1, step d

Sources & evidence

ORD record
ord-5ffd9d3aef6147898d04ee37a7919459
Source dataset
uspto-grants-1996_02
Patent number
US05492912

Reaction notes

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