反应详情

Hydrogen chloride gas is bubbled through a mixture of [(5-chloro-2-thenoyl)methyl]malononitrile (4.60 g, 20.5 mmol), ether and chloroform at a moderate rate for 20 minutes. The reaction mixture is poured into an ice-water mixture and extracted with ether. The combined organic extracts are dried over MgSO4 and concentrated in vacuo to give a brown solid. The solid is mixed with a hexane/ether solution and filtered to obtain the title product as a brown solid, mp >200° C.

1. extractionextracted with ether
2. dry with materialThe combined organic extracts are dried over MgSO4
3. concentrationconcentrated in vacuo
4. customto give a brown solid
5. filtrationfiltered