o-(Trifluoromethyl)benzaldehyde → HCID 18987466, compound

Participants

Reaction Steps

Using 4-chloro-2-(2-trifluoromethylbenzoyl)phenol [prepared from 2-bromo-4-chloro-(2methoxyethoxy)methoxybenzene and ortho(trifluoromethyl)benzaldehyde as the starting materials: m.p. 71°-72° C. (recrystallized from hexaneisopropyl ether)] in place of 4-chloro-2-benzoylphenol in Reference Example 1, substantially the same reactions as in Step 1 to Step 3 of Reference Example 1 were conducted to give the title compound. The compounds obtained in the respective steps and their physicochemical data are shown below.

Provenance & Evidence