4-Bromo-2-fluoro-1-(4-octoxyphenyl)benzene → 4,4"-Dioctyloxy-3,3'-difluoro-p-terphenyl

HRID 2396661Notes

Reaction equation

HRID 2396661 reaction equation
[CH2:1]([O:9][C:10]1[CH:15]=[CH:14][C:13](Br)=[CH:12][C:11]=1[F:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[CH2:18]([O:26][C:27]1[CH:32]=[CH:31][C:30]([C:33]2[CH:38]=[CH:37][C:36](Br)=[CH:35][C:34]=2[F:40])=[CH:29][CH:28]=1)[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25].C[C@@H](OC1C=CC(Br)=CC=1F)CCCCC.C(C1C=CC(C2C=CC(Br)=CC=2F)=CC=1)CCCCCCC>>[CH2:1]([O:9][C:10]1[CH:15]=[CH:14][C:13]([C:36]2[CH:37]=[CH:38][C:33]([C:30]3[CH:31]=[CH:32][C:27]([O:26][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])=[CH:28][CH:29]=3)=[C:34]([F:40])[CH:35]=2)=[CH:12][C:11]=1[F:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

5

Reactant 4

HCID 17156644-Bromo-2-fluoro-1-(4-octoxyphenyl)benzeneHCID 3581959Benzene, 4-bromo-2-fluoro-1-(octyloxy)-HCID 147662924-Octyl-2'-fluoro-4'-bromobiphenylHCID 14766296(R)-4-(1-methylhexyl)oxy-3-fluorobromobenzene

Product 1

HCID 147662784,4"-Dioctyloxy-3,3'-difluoro-p-terphenylYield 13.9%

Procedure

Except that 3.6 g of 4-octyloxy-3-fluorobromobenzene obtained in Example 3 (a) and 2.2 g of 4-octyloxy-2'-fluoro-4'-bromobiphenyl obtained in Example 2 (c) were used in place of 3.4 g of (R) -4-(1-methylhexyl)oxy-3-fluorobromobenzene and 2.2 g of 4-octyl-2'-fluoro-4 '-bromobiphenyl used in Example 1 (e), respectively, the operation was performed in the same manner as in Example 1 (e) to obtain 0.42 g (13.9%) of 4,4"-dioctyloxy-3,3 '-difluoro-p-terphenyl.

Sources & evidence

ORD record
ord-b9d4ec140a7143d9bab6c549882de81f
Source dataset
uspto-grants-1996_02
Patent number
US05494605

Reaction notes

Loading…