反应详情

31.0 g of 6-chloro-2-[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid, 22.0 g of 4,4'-dipyridylsulfide and 26.2 g of triphenylphosphine were suspended in 250 ml of toluene, and were violently stirred at room temperature for 2 hours. The reaction mixture was filtered, and the toluene was distilled off under reduced pressure. The residue thus obtained was purified by silica gel column chromatography to obtain 36.0 g of the above identified compound as a white crystal (yield 90%).

1. filtrationThe reaction mixture was filtered
2. distillationthe toluene was distilled off under reduced pressure
3. customThe residue thus obtained
4. customwas purified by silica gel column chromatography
5. customto obtain 36.0 g of the