1-(2-(6-Nitrotetralin-1-yl)ethyl)-4-(3,4-dimethoxyphenyl)piperidine → 1-(2-(6-Aminotetralin-1-yl) ethyl)-4-(3,4-dimethoxyphenyl)piperidine

Participants

Reaction Steps

A suspension of 3.2 g of 1-(2-(6-nitrotetralin-1-yl)ethyl)-4-(3,4-dimethoxyphenyl)piperidine in 50 ml of methanol is hydrogenated in the presence of 1.6 g of Pd/C (5%) until the absorption of hydrogen has come to a standstill. The catalyst is filtered off, and the filtrate is worked up in the customary manner and gives 1-(2-(6-aminotetralin-1-yl) ethyl)-4-(3,4-dimethoxyphenyl)piperidine.

Provenance & Evidence