HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 14651274, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 14651275 | HCID 14651275 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 14651274 | HCID 14651274 | 95.9% |
Reaction Steps
Employing ethyl 1-(2-thienyl)-5-methyl-6,7,8-trifluoro-1,4-dihydro-4 -oxoquinoline-3-carboxylate (1.05 g), conc. hydrochloric acid (10 ml) and 90% acetic acid (40 ml), the procedure of Reference Example 23 is repeated to give 1-(2-thienyl)-5-methyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid (0.93 g), as white powder, m.p. 221°-222.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05495020 |
| Source dataset | uspto-grants-1996_02 |
| ORD ID | ord-eee98288a8a94589b44c55d6fbff7db7 |
| Source note | uspto-grants-1996_02 |