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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2396993Generated: October 31, 2026

Imidazo(4,5-b)pyridine → HCID 22859140, compound

https://huagongshe.com/reaction/2396993

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazo(4,5-b)pyridineHCID 67504—
Reactant(1S)-[(2R)-(2,4-difluorophenyl)-2-oxiranyl]ethanolHCID 10631861—
ReactantHCID 22859141HCID 22859141—
ProductHCID 22859140HCID 2285914022.7%

Reaction Steps

Using (1S)-1-[(2R)-2-(2,4-difluorophenyl)-2-oxiranyl]ethanol (981 mg) and 1H-imidazo[4,5-b]pyridine (472 mg), (2S)-2-(2,4-difluorophenyl)-2-[(1R)-1-(3H-3-imidazo[4,5-b]pyridyl)ethyl]oxirane (501 mg) and (2S)-2-(2,4-difluorophenyl)-2-[(1R)-1-(1H-1-imidazo[4,5-b]pyridyl)ethyl]oxirane (271 mg) were obtained by the same way as in Reference Example 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05495024
Source datasetuspto-grants-1996_02
ORD IDord-cd7f84d56ea64516ad8c9ad910584751
Source noteuspto-grants-1996_02