4-Phenyl-2-butanol → (3-Fluorobutyl)benzene

HRID 2397085Notes

Reaction equation

HRID 2397085 reaction equation
CC(O)CCc1ccccc1.O=S(=O)(F)c1ccccn1>C1CCOC1.CC(C)(C)N=P(N1CCCC1)(N1CCCC1)N1CCCC1>CC(F)CCc1ccccc1

Participants

5

Reactant 2

HCID 613024-Phenyl-2-butanolHCID 11615218Pyridine-2-sulfonyl Fluoride

Product 1

HCID 14870238(3-Fluorobutyl)benzeneYield 53%

Reagents, catalysts & solvents 2

HCID 3856267tert-Butylimino-tri(pyrrolidino)phosphoraneReagentHCID 8028TetrahydrofuranSolvent2×

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-35cc28bd08704a0690572b74ee8bfe27
Source dataset
Deoxyfluorination screen
Original link
View source

Reaction notes

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