4-Phenyl-2-butanol → (3-Fluorobutyl)benzene

HRID 2397088Notes

Reaction equation

HRID 2397088 reaction equation
CC(O)CCc1ccccc1.O=S(=O)(F)c1ccc(C(F)(F)F)cc1>C1CCOC1.CN(C)C(=NC(C)(C)C)N(C)C>CC(F)CCc1ccccc1

Participants

5

Reactant 2

HCID 613024-Phenyl-2-butanolHCID 858282354-(Trifluoromethyl)benzenesulfonyl fluoride

Product 1

HCID 14870238(3-Fluorobutyl)benzeneYield 57%

Reagents, catalysts & solvents 2

HCID 35715812-tert-Butyl-1,1,3,3-tetramethylguanidineReagentHCID 8028TetrahydrofuranSolvent2×

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-f5527154a25141a7a32d71b6aa53c282
Source dataset
Deoxyfluorination screen
Original link
View source

Reaction notes

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