(1,1'-Biphenyl)-4-methanol → 1-(Fluoromethyl)-4-phenylbenzene

HRID 2397105Notes

Reaction equation

HRID 2397105 reaction equation
O=S(=O)(F)c1ccccn1.OCc1ccc(-c2ccccc2)cc1>C1CCOC1.CC(C)(C)N=P(N1CCCC1)(N1CCCC1)N1CCCC1>FCc1ccc(-c2ccccc2)cc1

Participants

5

Reactant 2

HCID 19186(1,1'-Biphenyl)-4-methanolHCID 11615218Pyridine-2-sulfonyl Fluoride

Product 1

HCID 860378541-(Fluoromethyl)-4-phenylbenzeneYield 77%

Reagents, catalysts & solvents 2

HCID 3856267tert-Butylimino-tri(pyrrolidino)phosphoraneReagentHCID 8028TetrahydrofuranSolvent2×

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-ec6c35edcf8044f78afce7f1d9a8b328
Source dataset
Deoxyfluorination screen
Original link
View source

Reaction notes

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