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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2397107Generated: November 1, 2026

(1,1'-Biphenyl)-4-methanol → 1-(Fluoromethyl)-4-phenylbenzene

https://huagongshe.com/reaction/2397107

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-4-methanolHCID 19186—
Reactant4-(Trifluoromethyl)benzenesulfonyl fluorideHCID 85828235—
Reagent7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-eneHCID 123583—
SolventTetrahydrofuranHCID 8028—
Product1-(Fluoromethyl)-4-phenylbenzeneHCID 8603785436%

Provenance & Evidence

DOI10.1021/jacs.8b01523
Source datasetDeoxyfluorination screen
ORD IDord-a7d18bbc11e74c8da5299b88cef3836c
Source noteDeoxyfluorination screen