HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2397108Generated: November 1, 2026
(1,1'-Biphenyl)-4-methanol → 1-(Fluoromethyl)-4-phenylbenzene
https://huagongshe.com/reaction/2397108
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (1,1'-Biphenyl)-4-methanol | HCID 19186 | — |
| Reactant | 4-(Trifluoromethyl)benzenesulfonyl fluoride | HCID 85828235 | — |
| Reagent | 2-tert-Butyl-1,1,3,3-tetramethylguanidine | HCID 3571581 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-(Fluoromethyl)-4-phenylbenzene | HCID 86037854 | 83% |
Provenance & Evidence
| DOI | 10.1021/jacs.8b01523 |
|---|
| Source dataset | Deoxyfluorination screen |
|---|
| ORD ID | ord-d67878c703d346319e9de002a25622e3 |
|---|
| Source note | Deoxyfluorination screen |
|---|
