HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2397154Generated: October 30, 2026
Perfluoro-1-butanesulfonyl fluoride → 1,2-Pyrrolidinedicarboxylic acid, 4-fluoro-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4R)-rel-
https://huagongshe.com/reaction/2397154
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Perfluoro-1-butanesulfonyl fluoride | HCID 67814 | — |
| Reactant | N-Boc-cis-4-hydroxy-L-proline methyl ester | HCID 10752873 | — |
| Reagent | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1,2-Pyrrolidinedicarboxylic acid, 4-fluoro-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4R)-rel- | HCID 10977773 | 59% |
Provenance & Evidence
| DOI | 10.1021/jacs.8b01523 |
|---|
| Source dataset | Deoxyfluorination screen |
|---|
| ORD ID | ord-e1c475b70bee4cc0adc37dd3eeb4b39e |
|---|
| Source note | Deoxyfluorination screen |
|---|
