2-Acetamido-6-methylpyridine → N-Ethyl-6-methylpyridin-2-amine

Participants

Reaction Steps

In a process for producing 6-ethylamino-2-picoline by reduction of 6-acetamido-2-picoline, the improvement which comprises reacting 6-acetamido-2-picoline with diborane in an inert non-polar solvent at about 0° to 70° C. to produce 6-ethylamino-2-picoline and using a low boiling petroleum solvent to separate the soluble 6-ethylamino-2-picoline from the insoluble 6-acetamido-2-picoline.

Provenance & Evidence