Ethylenediamine → HCID 21437376, compound

Participants

Reaction Steps

A mixture of 51 g (0.16 mole) of ethyl 5-(3,4-dimethoxyphenyl)-2-furimidate hydrochloride, 11 g (0.18 mole) of ethylenediamine, and 850 ml of absolute ethanol was refluxed for 5 hrs and then kept overnight at room temperature. The solid was recrystallized from acetic acid, washed with ether, and air dried to yield 33 g (65%) of 2-[5-(3,4-dimethoxyphenyl)-2-furyl]imidazoline hydrochloride. An analytical sample was prepared by recrystallizing a sample from methanol and drying in the vacuum pistol at the temperature of refluxing CHCl3, m.p. 291°-293°.

Provenance & Evidence