HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → HCID 12562517, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Reactant | 8-(trifluoromethyl)-1-(chloromethyl)-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine | HCID 21330780 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 12562517 | HCID 12562517 | — |
Reaction Steps
In the manner given in Example 1, potassium iodide and 8-(trifluoromethyl)-1-(chloromethyl)-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine in tetrahydrofuran is treated with cyclopropylamine to give 8-trifluoromethyl-1-(cyclopropylamino)methyl]-6(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04021441 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-237a0258424c4edd91c4ac685664755e |
| Source note | uspto-grants-1977_05 |