HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropylamine → HCID 21437261, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Reactant | HCID 20291813 | HCID 20291813 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 21437261 | HCID 21437261 | — |
Reaction Steps
In the manner given in Example 1,potassium iodide and 8-chloro-1-(chloromethyl)-6-(2,6-difluorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine in tetrahydrofuran is treated with cyclopropylamine to give 8-chloro-1-[(cyclopropylamino)methyl]-6-(2,6-difluorophenyl)4H-s-triazolo-[4,3-a][1,4]benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04021441 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-1c6ccc73ccbe4c559ab8434766f1ec54 |
| Source note | uspto-grants-1977_05 |