Potassium Iodide → HCID 68125377, compound

HRID 2397349Notes

Reaction equation

HRID 2397349 reaction equation
[CH2:1]([S:3][C:4]1[C:9]2[C:10]([C:20]3[CH:25]=[CH:24][CH:23]=[C:22]([Cl:26])[CH:21]=3)=[N:11][CH2:12][C:13]3[N:14]([C:15]([CH2:18]Cl)=[N:16][N:17]=3)[C:8]=2[CH:7]=[CH:6][CH:5]=1)[CH3:2].[I-].[K+].[CH2:29]([CH:32]=[CH:33][CH2:34][NH2:35])[CH2:30][CH3:31]>O1CCCC1>[CH2:1]([S:3][C:4]1[C:9]2[C:10]([C:20]3[CH:25]=[CH:24][CH:23]=[C:22]([Cl:26])[CH:21]=3)=[N:11][CH2:12][C:13]3[N:14]([C:15]([CH2:18][NH:35][CH2:34][CH2:33][CH2:32][CH2:29][CH:30]=[CH2:31])=[N:16][N:17]=3)[C:8]=2[CH:7]=[CH:6][CH:5]=1)[CH3:2]

Participants

5

Reactant 3

HCID 4875Potassium IodideHCID 21437245HCID 21437245, compoundHCID 53415109Hex-2-en-1-amine

Product 1

HCID 68125377HCID 68125377, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

In the manner given in Example 32, 7-(ethylthio)-1-(chloromethyl)-6-(m-chlorophenyl)-4H-s-triazolo[4,3-a]-[1,4]benzodiazepine, potassium iodide and propylallylamine in tetrahydrofuran are reacted to give 7-(ethylthio)-1-[(allylpropylamino)methyl]-6-(m-chlorophenyl)-4H-s-triazolo-[4,3-a][1,4]benzodiazepine.

Workup

  1. customare reacted

Sources & evidence

ORD record
ord-b6b7db8b585a4584a27bd40372c4370d
Source dataset
uspto-grants-1977_05
Patent number
US04021441

Reaction notes

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