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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2397392Generated: October 31, 2026

Cyclohexylamine → 4-(4'-Fluoro-4-biphenylyl)-4-hydroxy-butyric acid

https://huagongshe.com/reaction/2397392

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexylamineHCID 7965—
Reactant4-(4'-Fluoro-4-biphenylyl)-4-oxo-butyric acidHCID 10730870—
SolventWaterHCID 962—
Product4-(4'-Fluoro-4-biphenylyl)-4-hydroxy-butyric acidHCID 2143794354%

Reaction Steps

Prepared analogous to Example 25 from 4-(4'-fluoro-4-biphenylyl)-4-oxo-butyric acid. Melting point of the cyclohexylamine salt: 175°-177° C. (from water). Yield 54% of theory.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04021479
Source datasetuspto-grants-1977_05
ORD IDord-ade0dce29af44958a8d898ad79f83a23
Source noteuspto-grants-1977_05