Cyclohexylamine → HCID 21437919, compound

HRID 2397402Notes

Reaction equation

HRID 2397402 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:21])=[C:6]([C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:20])[CH2:15][CH2:16][C:17]([OH:19])=[O:18])=[CH:10][CH:9]=2)[CH:7]=1.C1(N)CCCCC1>C(OCC)(=O)C>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:21])=[C:6]([C:8]2[CH:9]=[CH:10][C:11]([CH:14]([OH:20])[CH2:15][CH2:16][C:17]([OH:19])=[O:18])=[CH:12][CH:13]=2)[CH:7]=1

Participants

4

Reactant 2

HCID 7965CyclohexylamineHCID 21437996HCID 21437996, compound

Product 1

HCID 21437919HCID 21437919, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

Prepared analogous to Example 25 from 4-(5'-chloro-2'-methyl-4-biphenylyl)-4-oxo-butyric acid. Yield: 90% of theory. Melting point of the cyclohexylamine salt: 114°-115° C. (from ethyl acetate).

Sources & evidence

ORD record
ord-ecb5871c8de142eda9578c9a7f80ab06
Source dataset
uspto-grants-1977_05
Patent number
US04021479

Reaction notes

Loading…