Water → HCID 21437954, compound

HRID 2397408Notes

Reaction equation

HRID 2397408 reaction equation
[Na].[Cl:2][C:3]1[CH:4]=[C:5]([C:10]2[CH:15]=[CH:14][C:13]([CH:16]([OH:22])/[CH:17]=[CH:18]/[C:19]([OH:21])=[O:20])=[CH:12][CH:11]=2)[CH:6]=[CH:7][C:8]=1[Cl:9].C1(N)CCCCC1.O>CO>[Cl:2][C:3]1[CH:4]=[C:5]([C:10]2[CH:11]=[CH:12][C:13]([CH:16]([OH:22])[CH2:17][CH2:18][C:19]([OH:21])=[O:20])=[CH:14][CH:15]=2)[CH:6]=[CH:7][C:8]=1[Cl:9]

Participants

6

Reactant 4

HCID 962WaterHCID 7965CyclohexylamineHCID 5360545SodiumHCID 21437929HCID 21437929, compound

Product 1

HCID 21437954HCID 21437954, compoundYield 62%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Prepared analogous to Example 46 from the sodium salt of the 4-(3',4'-dichloro-4-biphenylyl)-4-hydroxy-crotonic acid in methanol. Yield: 62% of theory. Melting point of the cyclohexylamine salt: 158°-159° C. (from water).

Sources & evidence

ORD record
ord-c6e3015c0b2b4ccb9590115b39e0c470
Source dataset
uspto-grants-1977_05
Patent number
US04021479

Reaction notes

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