反应详情

1.7 g (8.5 mmoles) of 2,3,5-tri-O-methyl-D-ribose are dissolved in 5 ml of absolute methanol. While stirring, 4.25 g (85 mmoles) of 100% hydrazine hydrate (dissolved in 5 ml of absolute methanol) are added. As a result slight heating occurs. Stirring is carried out for 2 days of room temperature. Following this methanol and superfluous hydrazine hydrate are removed in a rotary evaporator at room temperature (oil pump vacuum). Following this drying is carried out for one day under oil pump vacuum. A colorless oil is obtained. Yield: 1.6 g (92 %).

1. temperatureAs a result slight heating
2. stirringStirring
3. customare removed in a rotary evaporator at room temperature (oil pump vacuum)
4. waitis carried out for one day under oil pump vacuum
5. customA colorless oil is obtained