HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 21313321, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 4-Fluorobenzoyl chloride | HCID 67879 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | HCID 21313375 | HCID 21313375 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21313321 | HCID 21313321 | — |
Reaction Steps
Reaction of 3-{2-[2-(3-cyclohexylpropyl)piperidino]ethyl}-5-methoxy-2-methylindole with a mineral oil dispersion of sodium hydride in DMF and reaction of the resulting sodium salt with 4-fluorobenzoyl chloride affords 1-benzoyl-3-{2-[2-(3-cyclohexylpropyl)piperidino]ethyl}-5-methoxy-2-methylindole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04021431 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-733a0d4157d2420fab643f33a55e52b3 |
| Source note | uspto-grants-1977_05 |