HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → HCID 12781929, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | HCID 12781926 | HCID 12781926 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 12781929 | HCID 12781929 | 78.8% |
Reaction Steps
A mixture of 5-nitro-2-(3-bromomethyl-2-thienyl)-benzoxazole (5.0 g, 0.0147 mole) and morpholine (2.6 g, 0.03 mole) in 200 ml of benzene is refluxed for 24 hours. The precipitated morpholine hydrobromide is removed by filtration and the benzene evaporated under vacuum yielding 4.0 g of solid. Crystallization from ethanol yields 3.4 g of product, melting point 143°-145° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04022781 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-31097fcc04a14eccaf7b249439586afa |
| Source note | uspto-grants-1977_05 |