Ethylenediamine → HCID 21436377, compound

HRID 2397608Notes

Reaction equation

HRID 2397608 reaction equation
[ClH:1].[N+:2]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[O:15][C:14]([C:16](=[NH:20])OCC)=[CH:13][CH:12]=2)=[CH:7][CH:6]=1)([O-:4])=[O:3].[CH2:21](N)[CH2:22][NH2:23]>C(O)C>[ClH:1].[N+:2]([C:5]1[CH:6]=[CH:7][C:8]([C:11]2[O:15][C:14]([C:16]3[NH:20][CH2:21][CH2:22][N:23]=3)=[CH:13][CH:12]=2)=[CH:9][CH:10]=1)([O-:4])=[O:3]

Participants

4

Reactant 2

HCID 3301EthylenediamineHCID 21436379HCID 21436379, compound

Product 1

HCID 21436377HCID 21436377, compoundYield 86.4%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 39 g (0.13 mole) of ethyl 5-(4-nitrophenyl)-2-furimidate hydrochloride and 8.6 g (0.14 mole) of ethylenediamine in 400 ml of absolute ethanol was heated under reflux for 61/2 hr and stood in a refrigerator overnight. The yellow solid was collected by filtration and washed with anhydrous ether to give 33 g (85%) of product, m.p. > 300°.

Workup

  1. temperaturewas heated
  2. temperatureunder reflux for 61/2 hr
  3. customstood in a refrigerator overnight
  4. filtrationThe yellow solid was collected by filtration
  5. washwashed with anhydrous ether

Sources & evidence

ORD record
ord-fbf779a649924ec999a2b30e21a653c0
Source dataset
uspto-grants-1977_05
Patent number
US04022798

Reaction notes

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