Potassium Iodide → HCID 56636445, compound

Participants

Reaction Steps

To a solution of 6.6 g of potassium hydroxide (85%) and 0.2 g of potassium iodide in 100 ml of water is added 150 ml of methanol and 19.0 g of 9-hydroxy-2,8-dimethyl-4H-pyrido[ 1,2-a]-pyrimidin-4-one and the whole stirred for about 1 hour. To this is added 20.1 g of cinnamyl bromide dissolved in 20 ml of methanol. The mixture is stirred at room temperature for about 18 hours and then worked up to give 9-[ (cinnamyl)oxy] -2,8-dimethyl-4H-pyrido[ 1,2-a] pyrimidin-4-one.

Provenance & Evidence