HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 2-Bromo-6-methoxy-3-phenylbenzofuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 6-Methoxy-3-phenyl-benzofuran | HCID 5172700 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Bromo-6-methoxy-3-phenylbenzofuran | HCID 21436790 | — |
Reaction Steps
To a solution of 25 g (0.112 mole) of 6-methoxy-3 -phenylbenzofuran in 400 ml of dichloromethane is added over 1 hour dropwise with stirring 17.9 g (0.112 mole) of bromine in 20 ml of dichloromethane. The solution is washed with 200 ml of 10% aqueous sodium acetate, dried and evaporated to provide 2-bromo-6-methoxy-3-phenylbenzofuran as a dark oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04022908 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-49598e2dd0bc4a4ea305df3d36a9826d |
| Source note | uspto-grants-1977_05 |