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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2397881Generated: November 4, 2026

Guaiacol → 2-(2-Methoxyphenoxy)-1-phenylethanone

https://huagongshe.com/reaction/2397881

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGuaiacolHCID 460—
ReactantPhenacyl bromideHCID 6259—
ReactantPotassium CarbonateHCID 11430—
SolventAcetoneHCID 180—
Product2-(2-Methoxyphenoxy)-1-phenylethanoneHCID 355275—

Reaction Steps

A mixture of 1 mole of 2-methoxyphenol and 1 mole of potassium carbonate in acetone is heated at reflux while adding 1 mole of alpha-bromoacetophenone. The mixture is refluxed for several hours to provide alpha-(2-methoxyphenoxy)acetophenone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04022908
Source datasetuspto-grants-1977_05
ORD IDord-636de395bb4a48a6a847015aefffe9e1
Source noteuspto-grants-1977_05