HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Iodobenzoyl chloride → 2-Iodo-N-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)benzene-1-carboximidic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Iodobenzoyl chloride | HCID 69112 | — |
| Reactant | 2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amine | HCID 14171269 | — |
| Product | 2-Iodo-N-(2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)benzene-1-carboximidic acid | HCID 216600 | — |
Reaction Steps
5-Amino-2-methyl-1,2,3,4-tetrahydroisoquinoline was reacted with 2-iodobenzoyl chloride according to the procedure of Example 19 to yield 5-(2-iodobenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline; m.p. 215°-216.5° C. after purification from methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04022900 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-cbfa98e359de46aaa9e593f3a0295317 |
| Source note | uspto-grants-1977_05 |