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HRID2397973

反应详情

EQUATION

反应方程式

HRID 2397973 的结构方程式

REACTANTS

反应物

2
结构：O=C([O-])O.[Na+]
HCID516892

Sodium Bicarbonate

CHNaO3

结构：CCC(=O)OC[C@@]12C(=CCC[C@@H]1C)CC[C@H]1[C@@H]3CC[C@H](OC(=O)CC)[C@@]3(C)CC[C@@H]12
HCID70583889

未命名化合物

PRODUCTS

生成物

1
结构：CCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CCC[C@H](C)[C@]4(CO)[C@H]3CC[C@]12C
HCID70584765

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

1α-Methyl-4-androstene-17β,19-diol dipropionate is dissolved in a 10% aqueous methanol solution and one equivalent of sodium bicarbonate is added. The solution is stirred and heated at its reflux temperature for one hour and poured onto ice water with vigorous stirring. The precipitate is removed by filtration, air dried and crystallized from hexane to yield 1α-methyl-4-androstene-17β,19-diol 17-propionate.

WORKUP

后处理

  1. additionis added
  2. temperatureheated at its
  3. temperaturereflux temperature for one hour
  4. additionpoured onto ice water with vigorous stirring
  5. customThe precipitate is removed by filtration, air
  6. customdried
  7. customcrystallized from hexane