HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2397977Generated: October 29, 2026
Sodium Sulfite → 17beta-Hydroxy-1alpha-methyl-4-androsten-19-one propionate
https://huagongshe.com/reaction/2397977
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Sulfite | HCID 24437 | — |
| Reactant | 1alpha-Methyl-4-androstene-17beta,19-diol 17-propionate | HCID 70584765 | — |
| Reactant | Jones' reagent | HCID 131709961 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 17beta-Hydroxy-1alpha-methyl-4-androsten-19-one propionate | HCID 86734735 | — |
Reaction Steps
To a solution of 1α-methyl-4-androstene-17β,19-diol 17-propionate in dimethylformamide at 40° C. is rapidly added one equivalent of Jones Reagent. The solution is stirred for about 5 hours at 40° C., cooled and a 1% aqueous sodium sulfite solution is added. The precipitate is collected, washed well with water and crystallized from hexane to yield 17β-hydroxy-1α-methyl-4-androsten-19-one propionate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04022769 |
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| Source dataset | uspto-grants-1977_05 |
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| ORD ID | ord-c390a286b1c043d581cfd50232141393 |
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| Source note | uspto-grants-1977_05 |
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